The association between latent trauma and brain structure in children.

ABSTRACT: The developing brain is marked by high plasticity, which can lead to vulnerability to early life stressors. Previous studies indicate that childhood maltreatment is associated with structural aberrations across a number of brain regions. However, prior work is limited by small sample sizes, heterogeneous age groups, the examination of one structure in isolation, the confounding of different types of early life stressors, and not accounting for socioeconomic status. These limitations may contribute to high variability across studies. The present study aimed to investigate how trauma is specifically associated with cortical thickness and gray matter volume (GMV) differences by leveraging a large sample of children (N = 9270) from the Adolescent Brain Cognitive Development^SM Study

SUBMITTER: Jeong HJ 

PROVIDER: S-EPMC8068725 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature