Proteomic Analysis Identifies Potential Markers for Chicken Primary Follicle Development.

ABSTRACT: Follicles' development in chicken imparts a major impact on egg production. To enhance the egg-laying efficiency, comprehensive knowledge of different phases of follicular development is a prerequisite. Therefore, we used the tandem mass tag (TMT) based proteomic approach to find the genes involved in the primary follicular development of chicken. The primary follicles were divided into two groups-small primary follicles (81-150 μm) and developed primary follicles (300-500 μm). Differential expression analysis (fold change > 1.2, p-value < 0.05) revealed a total of 70 differentially expressed proteins (DEPs), of which 38 were upregulated and 32 were downregulated. Gene ontology (GO) enrichment analysis disclosed that DEPs were intricate with cellular protein localization, the establ

SUBMITTER: Wadood AA 

PROVIDER: S-EPMC8069082 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature