Ontology highlight
ABSTRACT:
SUBMITTER: Wijeratne T
PROVIDER: S-EPMC8069768 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Wijeratne Tissa T Sales Carmela C
Journal of clinical medicine 20210414 8
Ischemic Stroke precedes depression. Post-stroke depression (PSD) is a major driver for poor recovery, negative quality of life, poor rehabilitation outcomes and poor functional ability. In this systematic review, we analysed the inflammatory basis of post-stroke depression, which involves bioenergetic failure, deranged iron homeostasis (calcium influx, Na influx, potassium efflux etc), excitotoxicity, acidotoxicity, disruption of the blood brain barrier, cytokine-mediated cytotoxicity, reactive ...[more]