Terpenoid Biosynthesis Dominates among Secondary Metabolite Clusters in Mucoromycotina Genomes.

ABSTRACT: Early-diverging fungi harbour unprecedented diversity in terms of living forms, biological traits and genome architecture. Before the sequencing era, non-Dikarya fungi were considered unable to produce secondary metabolites (SM); however, this perspective is changing. The main classes of secondary metabolites in fungi include polyketides, nonribosomal peptides, terpenoids and siderophores that serve different biological roles, including iron chelation and plant growth promotion. The same classes of SM are reported for representatives of early-diverging fungal lineages. Encouraged by the advancement in the field, we carried out a systematic survey of SM in Mucoromycotina and corroborated the presence of various SM clusters (SMCs) within the phylum. Among the core findings, considerab

SUBMITTER: Koczyk G 

PROVIDER: S-EPMC8070225 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature