Multiresponsive Cellulose Nanocrystal Cross-Linked Copolymer Hydrogels for the Controlled Release of Dyes and Drugs.

ABSTRACT: Multiresponsive hydrogels have attracted tremendous interest due to their promising applications in tissue engineering, wearable devices, and flexible electronics. In this work, we report a multiresponsive upper critical solution temperature (UCST) composite hydrogel based on poly (acrylic acid-co-acrylamide), PAAc-co-PAAm, sequentially cross-linked by acid-hydrolysis cellulose nanocrystals (CNCs). Scanning electron microscopy (SEM) observations demonstrated that the hydrogels are formed by densely cross-linked porous structures. The PAAc/PAAm/CNC hybrid hydrogels exhibit swelling and shrinking properties that can be induced by multiple stimuli, including temperature, pH, and salt concentration. The driving force of the volume transition is the formation and dissociation of hydrogen bonds

SUBMITTER: Jiang Y 

PROVIDER: S-EPMC8070268 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature