Assessment of the endocrine disrupting properties of bisphenol AF: a case study applying the European regulatory criteria and guidance.

ABSTRACT:

Background

Scientific criteria to identify endocrine disruptors (ED) was recently implemented for plant protection products (PPP) and biocidal products (BP). A guidance document has been published by ECHA and EFSA in the context of ED criteria for PPPs and BPs.

Methods

In the present work, a case study was performed on Bisphenol AF (BPAF) to explore the application of the EU criteria and EFSA/ECHA guidance document for the ED assessment of a non-pesticide chemical regulated under REACH. A data dossier was built by a systematic literature search (Web of Science, Pubmed, Embase; n = 511), title/abstract screening (n = 124) and full text examination (n = 88). All the information was extracted and systematically reported for 309 parameters (100 for adversity; 209 for endocrine a

SUBMITTER: Escriva L 

PROVIDER: S-EPMC8070297 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature