Effect of heart rate on left ventricular longitudinal myocardial function in type 2 diabetes mellitus.

ABSTRACT:

Background

Left ventricular (LV) longitudinal myocardial dysfunction is considered a marker of preclinical LV dysfunction in patients with type 2 diabetes mellitus (T2DM). High heart rate (HR) is associated with cardiovascular outcomes, but the effect of HR on LV longitudinal myocardial function in T2DM patients is uncertain.

Methods

We studied 192 T2DM patients with preserved LV ejection fraction (LVEF), and 81 age-, sex-, and LVEF-matched healthy volunteers. HR was measured as the average HR during echocardiography, and high HR was defined as resting HR ≥ 70 beats/minute. LV longitudinal myocardial function was assessed as global longitudinal strain (GLS). The predefined cutoff for subclinical LV dysfunction was set at GLS < 18%.

Results

GLS in T2DM patients with hi

SUBMITTER: Yamauchi Y 

PROVIDER: S-EPMC8070299 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature