Towards Novel Non-Invasive Colorectal Cancer Screening Methods: A Comprehensive Review.

ABSTRACT: Colorectal cancer (CRC) is one of the leading cancer-related causes of death in the world. Since the 70s, many countries have adopted different CRC screening programs, which has resulted in a decrease in mortality. However, current screening test options still present downsides. The commercialized stool-based tests present high false-positive rates and low sensitivity, which negatively affects the detection of early stage carcinogenesis. The gold standard colonoscopy has low uptake due to its invasiveness and the perception of discomfort and embarrassment that the procedure may bring. In this review, we collected and described the latest data about alternative CRC screening techniques that can overcome these disadvantages. Web of Science and PubMed were employed as search engines for studi

SUBMITTER: Ferrari A 

PROVIDER: S-EPMC8070308 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature