The Art of Designing DNA Nanostructures with CAD Software.

ABSTRACT: Since the arrival of DNA nanotechnology nearly 40 years ago, the field has progressed from its beginnings of envisioning rather simple DNA structures having a branched, multi-strand architecture into creating beautifully complex structures comprising hundreds or even thousands of unique strands, with the possibility to exactly control the positions down to the molecular level. While the earliest construction methodologies, such as simple Holliday junctions or tiles, could reasonably be designed on pen and paper in a short amount of time, the advent of complex techniques, such as DNA origami or DNA bricks, require software to reduce the time required and propensity for human error within the design process. Where available, readily accessible design software catalyzes our ability to bring t

SUBMITTER: Glaser M 

PROVIDER: S-EPMC8071251 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature