Predictors of Single Bronchodilation Treatment Response for COPD: An Observational Study with the Trace Database Cohort.

ABSTRACT: Chronic obstructive pulmonary disease (COPD) patients constitute a heterogeneous population in terms of treatment response. Our objective was to identify possible predictive factors of response to treatment with single bronchodilation monotherapy in patients diagnosed with COPD. The Time-based Register and Analysis of COPD Endpoints (TRACE; clinicaltrials.gov NCT03485690) is a prospective cohort of COPD patients who have been attending annual visits since 2012. Patients who were kept on a single bronchodilator during the first year of follow-up were selected. The responders were defined according to all of the following variables: any improvement in morning post-dose forced expiratory volume in 1 s or deterioration <100 mL, no change or improvement in dyspnea score, and no occurrence of ex

SUBMITTER: Carrasco Hernandez L 

PROVIDER: S-EPMC8071403 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature