Ultrasonography predicts the results of labial salivary gland biopsy in patients with suspected Sjogren's syndrome: a matrix risk model.

ABSTRACT:

Objective

Although a positive result of labial salivary gland biopsy (LSGB) is critical for the diagnosis of Sjögren's syndrome, rheumatologists prefer assessing the non-invasive objective items and hope to learn the predicted probability of positive LSGB before referring patients with suspected Sjögren's syndrome to receive biopsy. This study aimed to explore the predictive value of combined B-mode ultrasonography (US) and shear-wave elastography (SWE) examination on LSGB results.

Methods

A derivation cohort and later a validation cohort of patients with suspected Sjögren's syndrome were recruited. All participants received clinical assessments, B-mode US and SWE examination on bilateral parotid and submandibular glands before LSGB. Positive LSGB was defined by a focus scor

SUBMITTER: Mo YQ 

PROVIDER: S-EPMC8071977 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature