Accelerated vaccine rollout is imperative to mitigate highly transmissible COVID-19 variants.

ABSTRACT:

Background

More contagious variants of SARS-CoV-2 have emerged around the world, sparking concerns about impending surge in cases and severe outcomes. Despite the development of effective vaccines, rollout has been slow. We evaluated the impact of accelerated vaccine distribution on curbing the disease burden of novel SARS-CoV-2 variants.

Methods

We used an agent-based model of SARS-CoV-2 transmission and vaccination to simulate the spread of novel variants with S-Gene Target Failure (SGTF) in addition to the original strain. We incorporated age-specific risk and contact patterns and implemented a two-dose vaccination campaign in accord with CDC-recommended prioritization. As a base case, we projected hospitalizations and deaths at a daily vaccination rate of 1 million doses

SUBMITTER: Sah P 

PROVIDER: S-EPMC8072134 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature