Vaginal Microbiome Is Associated With Vulvodynia, Vulvar Pain Syndrome: A Case-Control Study.

ABSTRACT:

Introduction

Vulvodynia, vulvar pain syndrome, is defined as vulvar pain of at least a 3-month duration without a clear identifiable cause, which may have associated factor and the etiology and treatment of this challenging disease is still unclear. Dyspareunia is a relevant symptom of patients with vulvodynia. Vaginal microbiome has known an important role in local immune-inflammatory responses and it may be important pathogenic mechanism in vulvodynia.

Aim

The objective of this study was to investigate the association of vaginal microbiome and vulvodynia.

Methods

We analyzed the microbial compositions of the vestibule and vagina among women with clinically diagnosed vulvodynia (n = 22) and age-matched healthy controls (n = 22) without vulvodynia. The compositions of

SUBMITTER: Park SY 

PROVIDER: S-EPMC8072171 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature