Cardiac biomarkers in acute respiratory distress syndrome: a systematic review and meta-analysis.

ABSTRACT:

Background

Acute respiratory distress syndrome (ARDS) is a leading cause of morbidity and mortality in the intensive care unit. Biochemical markers of cardiac dysfunction are associated with high mortality in many respiratory conditions. The aim of this systematic review is to examine the link between elevated biomarkers of cardiac dysfunction in ARDS and mortality.

Methods

A systematic review of MEDLINE, EMBASE, Web of Science and CENTRAL databases was performed. We included studies of adult intensive care patients with ARDS that reported the risk of death in relation to a measured biomarker of cardiac dysfunction. The primary outcome of interest was mortality up to 60 days. A random-effects model was used for pooled estimates. Funnel-plot inspection was done to evaluate pu

SUBMITTER: Jayasimhan D 

PROVIDER: S-EPMC8072305 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature