The Structure of Relationships between the Human Exposome and Cardiometabolic Health: The Million Veteran Program.

ABSTRACT: The exposome represents the array of dietary, lifestyle, and demographic factors to which an individual is exposed. Individual components of the exposome, or groups of components, are recognized as influencing many aspects of human physiology, including cardiometabolic health. However, the influence of the whole exposome on health outcomes is poorly understood and may differ substantially from the sum of its individual components. As such, studies of the complete exposome are more biologically representative than fragmented models based on subsets of factors. This study aimed to model the system of relationships underlying the way in which the diet, lifestyle, and demographic components of the overall exposome shapes the cardiometabolic risk profile. The current study included 36,49

SUBMITTER: Ivey KL 

PROVIDER: S-EPMC8073795 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature