Menopausal Hormone Therapy and Risk of Diverticulitis.

ABSTRACT:

Introduction

Diverticulitis is a significant cause of morbidity among older women, and little attention has been paid to understanding its etiology. We have shown that menopausal hormone therapy (MHT) is associated with the risk of inflammatory bowel disease. In this study, we prospectively examined the association between MHT and the risk of incident diverticulitis.

Methods

We studied 65,367 postmenopausal women enrolled in the Nurses' Health Study who provided detailed information on hormone use and other medical and lifestyle factors biennially, and on diet every 4 years. Between 2008 and 2014, participants reported any episodes of diverticulitis that required antibiotics and the date of occurrence. We used Cox proportional hazards regression models to estimate multivaria

SUBMITTER: Jovani M 

PROVIDER: S-EPMC8074020 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature