Ontology highlight
ABSTRACT:
SUBMITTER: Mackwood O
PROVIDER: S-EPMC8075581 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Mackwood Owen O Naumann Laura B LB Sprekeler Henning H
eLife 20210426
Understanding the connectivity observed in the brain and how it emerges from local plasticity rules is a grand challenge in modern neuroscience. In the primary visual cortex (V1) of mice, synapses between excitatory pyramidal neurons and inhibitory parvalbumin-expressing (PV) interneurons tend to be stronger for neurons that respond to similar stimulus features, although these neurons are not topographically arranged according to their stimulus preference. The presence of such excitatory-inhibit ...[more]