Effect of respiratory inhibitors and quinone analogues on the aerobic electron transport system of Eikenella corrodens.

ABSTRACT: The effects of respiratory inhibitors, quinone analogues and artificial substrates on the membrane-bound electron transport system of the fastidious β-proteobacterium Eikenella corrodens grown under O₂-limited conditions were studied. NADH respiration in isolated membrane particles were partially inhibited by rotenone, dicoumarol, quinacrine, flavone, and capsaicin. A similar response was obtained when succinate oxidation was performed in the presence of thenoyltrifluoroacetone and N,N'-dicyclohexylcarbodiimide. NADH respiration was resistant to site II inhibitors and cyanide, indicating that a percentage of the electrons transported can reach O₂ without the bc₁ complex. Succinate respiration was sensitive to myxothiazol, antimycin A and 2-heptyl-4-hydroxyq

SUBMITTER: Jaramillo-Lanchero RD 

PROVIDER: S-EPMC8076288 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature