Evidence of SARS-CoV-2 reinfection within the same clade in Ecuador: A case study.

ABSTRACT:

Objectives

To date, reported SARS-CoV-2 reinfection cases are mainly from strains belonging to different clades. As the pandemic advances, a few lineages have become dominant in certain areas leading to reinfections by similar strains. Here, we report a reinfection case within the same clade of the initial infection in a symptomatic 28-year-old-male in Quito-Ecuador.

Methods

Infection was detected by reverse transcription-polymerase chain reaction, and immune response evaluated by antibody testing. Whole-genome sequencing was performed and phylogenetic analysis conducted to determine relatedness.

Results

Both the infection and the reinfection strains were assigned as Nextstrain 20B, Pangolin lineage B.1.1 and GISAID clade O. Our analysis indicated 4-6 fold more nucleo

SUBMITTER: Sevillano G 

PROVIDER: S-EPMC8078048 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature