Mild therapeutic hypothermia after out-of-hospital cardiac arrest: What does really matter?

ABSTRACT:

Background

Mild therapeutic hypothermia (MTH) is a recommended treatment of comatose patients after out-of-hospital cardiac arrest (OHCA). The aim of the study was to examine determinants of clinical outcome in OHCA survivors treated with MTH and variables associated with MTH induction time.

Methods

Presented herein is an analysis of combined results from a retrospective and a prospective observational study which included 90 OHCA survivors treated with MTH from January 2010 to March 2018. Multivariate regression analysis was performed to determine variables associated with poor neurologic outcome (Cerebral Performance Category 3-5), mortality, and prolonged induction time.

Results

At hospital discharge, 59 (65.6%) patients were alive, of whom 36 (61%) had a good neur

SUBMITTER: Ratajczak J 

PROVIDER: S-EPMC8078942 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature