Risk phenotypes of diabetes and association with COVID-19 severity and death: a living systematic review and meta-analysis.

ABSTRACT:

Aims/hypothesis

Diabetes has been identified as a risk factor for poor prognosis of coronavirus disease-2019 (COVID-19). The aim of this study is to identify high-risk phenotypes of diabetes associated with COVID-19 severity and death.

Methods

This is the first edition of a living systematic review and meta-analysis on observational studies investigating phenotypes in individuals with diabetes and COVID-19-related death and severity. Four different databases were searched up to 10 October 2020. We used a random effects meta-analysis to calculate summary relative risks (SRR) with 95% CI. The certainty of evidence was evaluated by the GRADE tool.

Results

A total of 22 articles, including 17,687 individuals, met our inclusion criteria. For COVID-19-related death among in

SUBMITTER: Schlesinger S 

PROVIDER: S-EPMC8079163 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature