Working Memory Training Effects on White Matter Integrity in Young and Older Adults.

ABSTRACT:

Objectives

Working memory is essential for daily life skills like reading comprehension, reasoning, and problem-solving. Healthy aging of the brain goes along with working memory decline that can affect older people's independence in everyday life. Interventions in the form of cognitive training are a promising tool for delaying age-related working memory decline, yet the underlying structural plasticity of white matter is hardly studied.

Methods

We conducted a longitudinal diffusion tensor imaging study to investigate the effects of an intensive four-week adaptive working memory training on white matter integrity quantified by global and tract-wise mean diffusivity. We compared diffusivity measures of fiber tracts that are associated with working memory of 32 young and 20 o

SUBMITTER: Dziemian S 

PROVIDER: S-EPMC8079651 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature