Effectiveness of dietary interventions on cardio-metabolic risk factors in patients with nonalcoholic fatty liver disease: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Dietary modification is considered as one of the main strategies in the management of nonalcoholic fatty liver disease (NAFLD). The objective of this study was to systematically investigate the effect of dietary interventions on the cardio-metabolic risk factors, including lipid profile and insulin resistance in this population.

Methods

We searched electronic databases of PubMed and Scopus until January 2020 and included randomized controlled trials that compared the effect of dietary modifications vs. control on lipid profile and insulin resistance in patients with NAFLD. The random-effect analysis was performed to calculate pooled weighted mean differences (WMD).

Results

Our finding showed that serum triglycerides (TG) (n=5, WMD -38.50 mg/dL, 95% confiden

SUBMITTER: Ghadimi M 

PROVIDER: S-EPMC8079875 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature