The relationship between hippocampal-dependent task performance and hippocampal grey matter myelination and iron content.

ABSTRACT: Individual differences in scene imagination, autobiographical memory recall, future thinking and spatial navigation have long been linked with hippocampal structure in healthy people, although evidence for such relationships is, in fact, mixed. Extant studies have predominantly concentrated on hippocampal volume. However, it is now possible to use quantitative neuroimaging techniques to model different properties of tissue microstructure in vivo such as myelination and iron. Previous work has linked such measures with cognitive task performance, particularly in older adults. Here we investigated whether performance on scene imagination, autobiographical memory, future thinking and spatial navigation tasks was associated with hippocampal grey matter myelination or iron content in young, hea

SUBMITTER: Clark IA 

PROVIDER: S-EPMC8079931 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature