Utility of post mastectomy radiotherapy among patients with T1/ T2 N1 disease: A retrospective cohort study.

ABSTRACT:

Background

Pakistan has the highest incidence of breast cancer among Asian Countries but there is insufficient representation of local data addressing breast cancer treatment and outcome. We sought to determine the role of post-mastectomy radiotherapy (PMRT) in T1- T2 breast cancer with 1-3 positive axillary lymph nodes.

Methods

Data was reviewed retrospectively of total 755 patients out of which 291 received PMRT and 464 did not from two large breast cancer centres.

Results

With a median follow up of 78 months, 4 (4.5%) patients developed loco regional recurrence (LRR) in the PMRT group while a substantial number 74 (24.4%) recurred in the non PMRT group (p = 0.000). Loco regional free survival rate (LRFS) and overall survival rate (OS) was significantly better for P

SUBMITTER: Vohra LM 

PROVIDER: S-EPMC8079936 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature