EPA guidance on assessment of negative symptoms in schizophrenia.

ABSTRACT:

Background

During the last decades, a renewed interest for negative symptoms (NS) was brought about by the increased awareness that they interfere severely with real-life functioning, particularly when they are primary and persistent.

Methods

In this guidance paper, we provide a systematic review of the evidence and elaborate several recommendations for the conceptualization and assessment of NS in clinical trials and practice.

Results

Expert consensus and systematic reviews have provided guidance for the optimal assessment of primary and persistent negative symptoms; second-generation rating scales, which provide a better assessment of the experiential domains, are available; however, NS are still poorly assessed both in research and clinical settings.This European P

SUBMITTER: Galderisi S 

PROVIDER: S-EPMC8080207 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature