Natural course of metabolically healthy phenotype and risk of developing Cardiometabolic diseases: a three years follow-up study.

ABSTRACT:

Background

Whether the metabolically healthy obese (MHO) phenotype is a single, stable or a transitional, fluctuating state is currently unknown. The Mexican-Mestizo population has a genetic predisposition for the development of type 2 diabetes (T2D) and other cardiometabolic complications. Little is known about the natural history of metabolic health in this population. The aim of this study was to analyze the transitions over time among individuals with different degrees of metabolic health and body mass index, and evaluate the incidence of cardiometabolic outcomes according to phenotype.

Methods

The study population consisted of a metabolic syndrome cohort with at least 3 years of follow up. Participants were apparently-healthy urban Mexican adults ≥20 years with a body m

SUBMITTER: Elias-Lopez D 

PROVIDER: S-EPMC8080399 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature