Potential impact of introducing vaccines against COVID-19 under supply and uptake constraints in France: A modelling study.

ABSTRACT:

Background

The accelerated vaccine development in response to the COVID-19 pandemic should lead to a vaccine being available early 2021, albeit in limited supply and possibly without full vaccine acceptance. We assessed the short-term impact of a COVID-19 immunization program with varying constraints on population health and non-pharmaceutical interventions (NPIs) needs.

Methods

A SARS-CoV-2 transmission model was calibrated to French epidemiological data. We defined several vaccine implementation scenarios starting in January 2021 based on timing of discontinuation of NPIs, supply and uptake constraints, and their relaxation. We assessed the number of COVID-19 hospitalizations averted, the need for and number of days with NPIs in place over the 2021-2022 period.

Results<

SUBMITTER: Coudeville L 

PROVIDER: S-EPMC8081204 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature