Evaluation of association studies and a systematic review and meta-analysis of CYP1A1 T3801C and A2455G polymorphisms in breast cancer risk.

ABSTRACT:

Background

Nine previous meta-analyses have been published to analyze the CYP1A1 T3801C and A2455G polymorphisms with BC risk. However, they did not assess the credibility of statistically significant associations. In addition, many new studies have been reported on the above themes. Hence, we conducted an updated systematic review and meta-analysis to further explore the above issues.

Objectives

To explore the association on the CYP1A1 T3801C and A2455G polymorphisms with BC risk.

Methods

Preferred Reporting Items for Systematic Reviews and Meta-Analyses (The PRISMA) were used.

Results

In this study, there were 63 case-control studies from 56 publications on the CYP1A1 T3801C polymorphism (including 20,825 BC cases and 25,495 controls) and 51 case-control stud

SUBMITTER: Yang C 

PROVIDER: S-EPMC8081265 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature