Management of Trichomoniasis in the Setting of 5-Nitroimidazole Hypersensitivity.

ABSTRACT:

Abstract

Metronidazole and other 5-nitroimidazoles are the mainstay of Trichomonas vaginalis treatment, with few efficacious and safe treatment options available outside of this class. Patients with trichomoniasis and a history of a clinically confirmed hypersensitivity reaction to 5-nitroimidazoles present a management challenge for clinicians. The first step in managing such patients is metronidazole desensitization. In situations where this cannot be performed or tolerated, treatment with alternative regimens outside of the 5-nitroimidazole class, such as intravaginal boric acid or paromomycin, may be possible.

SUBMITTER: Van Gerwen OT 

PROVIDER: S-EPMC8081757 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature