Toenail Psoriasis during Ustekinumab Therapy: Results and Limitations.

ABSTRACT:

Background

Nail psoriasis is a common clinically significant symptom of psoriasis. However, few studies have focused on the characteristics and course of toenail psoriasis.

Objective

To investigate the treatment response of toenail psoriasis during a 52-week period of ustekinumab use.

Methods

Patients were evaluated using the Nail Psoriasis Severity Index (NAPSI) at every injection visit. NAPSI score changes throughout the treatment were analyzed. The treatment response in each toenail and each NAPSI characteristic was also analyzed.

Results

A total of 22 patients with chronic plaque psoriasis with concomitant toenail psoriasis were examined. Several characteristics such as ridging or onychomycosis that mimic psoriasis or hinder the evaluation were identified.

SUBMITTER: Yang S 

PROVIDER: S-EPMC8082003 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature