Suppression of Escherichia coli Growth Dynamics via RNAs Secreted by Competing Bacteria.

ABSTRACT: With the discovery of secreted RNAs, it has become apparent that the biological role of regulatory oligonucleotides likely goes beyond the borders of individual cells. However, the mechanisms of their action are still comprehended only in general terms and mainly for eukaryotic microRNAs, which can interfere with mRNAs even in distant recipient cells. It has recently become clear that bacterial cells lacking interference systems can also respond to eukaryotic microRNAs that have targets in their genomes. However, the question of whether bacteria can perceive information transmitted by oligonucleotides secreted by other prokaryotes remained open. Here we evaluated the fraction of short RNAs secreted by Escherichia coli during individual and mixed growth with Rhodospirillum rubrum

SUBMITTER: Markelova N 

PROVIDER: S-EPMC8082180 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature