Stool Banking for Fecal Microbiota Transplantation: Methods and Operations at a Large Stool Bank.

ABSTRACT:

Objectives

Fecal microbiota transplantation (FMT) is a recommended therapy for recurrent Clostridioides difficile infection and is being investigated as a potential therapy for dozens of microbiota-mediated indications. Stool banks centralize FMT donor screening and FMT material preparation with the goal of expanding access to FMT material while simultaneously improving its safety, quality, and convenience. Although there are published consensuses on donor screening guidelines, there are few reports about the implementation of those guidelines in functioning stool banks.

Methods

To help inform consensus standards with data gathered from real-world settings and, in turn, to improve patient care, here we describe the general methodology used in 2018 by OpenBiome, a larg

SUBMITTER: Chen J 

PROVIDER: S-EPMC8082449 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature