Pharmacotherapy in pediatric obesity: current evidence and landscape.

ABSTRACT:

Purpose of review

Childhood obesity is escalating globally. Lifestyle and behavioral changes, which are the frequently used interventions in clinical practice, lead to only modest improvements in children with established obesity. Bariatric surgery is currently the most effective obesity treatment but has very limited utilization in pediatric obesity and is preferentially used for children with worsening comorbidities. There exists a massive treatment gap for children suffering with obesity especially after the failure of lifestyle modifications. Pharmacotherapy that is an established management tool in adults is very infrequently used in children. Only two medications, Phentermine and Orlistat are approved by the Food and Drug Administration (FDA) for use in adolescent obesity. He

SUBMITTER: Singhal V 

PROVIDER: S-EPMC8082722 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature