Insights about the epidemiology of Salmonella Typhimurium isolates from different sources in Brazil using comparative genomics.

ABSTRACT:

Background

Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium) is an important zoonotic agent worldwide. The aim of this work was to compare genetically 117 S. Typhimurium isolated from different sources over 30 years in Brazil using different genomics strategies.

Results

The majority of the 117 S. Typhimurium strains studied were grouped into a single cluster (≅ 90%) by the core genome multilocus sequence typing and (≅ 77%) by single copy marker genes. The phylogenetic analysis based on single nucleotide polymorphism (SNP) grouped most strains from humans into a single cluster (≅ 93%), while the strains isolated from food and swine were alocated into three clusters. The different orthologous protein clusters found for some S. Typhimurium isolated from h

SUBMITTER: Seribelli AA 

PROVIDER: S-EPMC8082823 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature