Co-occurring hydrocephalus in autism spectrum disorder: a Danish population-based cohort study.

ABSTRACT:

Background

The association between autism spectrum disorder and hydrocephalus is not well understood, despite demonstrated links between autism spectrum disorder and cerebrospinal fluid abnormalities. Based on the hypothesis that autism spectrum disorder and hydrocephalus may, at least in some cases, be two manifestations of a shared congenital brain pathology, we investigated the potential association between autism spectrum disorder and hydrocephalus in a large Danish population-based cohort.

Methods

Patients and controls were obtained from the Lundbeck Foundation Initiative for Integrative Psychiatric Research iPSYCH2012 case-cohort, which includes all patients with selected psychiatric disorders born in Denmark 1981-2005 along with randomly selected population controls (

SUBMITTER: Munch TN 

PROVIDER: S-EPMC8082886 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature