The Promise of Improved Adherence With Long-Acting Antiretroviral Therapy: What Are the Data?

ABSTRACT: As with other chronic conditions, adherence to daily medications remains a challenge for many individuals living with HIV due to structural, behavioral, and social barriers. Unfortunately, high levels of adherence to antiretroviral therapy are required to maintain virologic suppression. Alternative approaches are being explored to decrease the burden of daily pill administration, including long-acting injectable, oral, and implantable products. Phase 3 data support the efficacy of nanoformulated injectable cabotegravir and rilpivirine for HIV treatment in patients with undetectable viremia, but we have yet to learn how this strategy may benefit those with medication adherence challenges. Despite this, the affected community and HIV providers are very interested in exploring the role of lon

SUBMITTER: Scarsi KK 

PROVIDER: S-EPMC8082990 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature