Kidney involvement in multisystem inflammatory syndrome in children: a pediatric nephrologist's perspective.

ABSTRACT: The initial report of the multisystem inflammatory syndrome in children (MIS-C) was from the UK in April 2020; since then, cases have been reported worldwide. Renal involvement has been seen commonly, ranging from 10% to 46%. Kidney involvement following severe acute respiratory syndrome coronavirus 2 infection in children with MIS-C is more common than initially thought and is associated with higher morbidity and mortality. There are several reports of a direct viral tropism of coronavirus disease 2019 and MIS-C-associated renal damage. This study's objective was to systematically review the current understanding of kidney involvement in children suffering from MIS-C. Based on our systemic literature search, 19 studies have either partially or fully discussed kidney involvement in MIS-C p

SUBMITTER: Sethi SK 

PROVIDER: S-EPMC8083308 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature