Dataset Information

Detecting Rapid Spread of SARS-CoV-2 Variants, France, January 26-February 16, 2021.

ABSTRACT: Variants of severe acute respiratory syndrome coronavirus 2 raise concerns regarding the control of coronavirus disease epidemics. We analyzed 40,000 specific reverse transcription PCR tests performed on positive samples during January 26-February 16, 2021, in France. We found high transmission advantage of variants and more advanced spread than anticipated.

SUBMITTER: Haim-Boukobza S

PROVIDER: S-EPMC8084510 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Detecting Rapid Spread of SARS-CoV-2 Variants, France, January 26-February 16, 2021.

Haim-Boukobza Stéphanie S Roquebert Bénédicte B Trombert-Paolantoni Sabine S Lecorche Emmanuel E Verdurme Laura L Foulongne Vincent V Selinger Christian C Michalakis Yannis Y Sofonea Mircea T MT Alizon Samuel S

Emerging infectious diseases 20210326 5

Variants of severe acute respiratory syndrome coronavirus 2 raise concerns regarding the control of coronavirus disease epidemics. We analyzed 40,000 specific reverse transcription PCR tests performed on positive samples during January 26-February 16, 2021, in France. We found high transmission advantage of variants and more advanced spread than anticipated. ...[more]

PMID: 33769253

Similar Datasets

Project description:From January 21 through February 23, 2020, public health agencies detected 14 U.S. cases of coronavirus disease 2019 (COVID-19), all related to travel from China (1,2). The first nontravel-related U.S. case was confirmed on February 26 in a California resident who had become ill on February 13 (3). Two days later, on February 28, a second nontravel-related case was confirmed in the state of Washington (4,5). Examination of four lines of evidence provides insight into the timing of introduction and early transmission of SARS-CoV-2, the virus that causes COVID-19, into the United States before the detection of these two cases. First, syndromic surveillance based on emergency department records from counties affected early by the pandemic did not show an increase in visits for COVID-19-like illness before February 28. Second, retrospective SARS-CoV-2 testing of approximately 11,000 respiratory specimens from several U.S. locations beginning January 1 identified no positive results before February 20. Third, analysis of viral RNA sequences from early cases suggested that a single lineage of virus imported directly or indirectly from China began circulating in the United States between January 18 and February 9, followed by several SARS-CoV-2 importations from Europe. Finally, the occurrence of three cases, one in a California resident who died on February 6, a second in another resident of the same county who died February 17, and a third in an unidentified passenger or crew member aboard a Pacific cruise ship that left San Francisco on February 11, confirms cryptic circulation of the virus by early February. These data indicate that sustained, community transmission had begun before detection of the first two nontravel-related U.S. cases, likely resulting from the importation of a single lineage of virus from China in late January or early February, followed by several importations from Europe. The widespread emergence of COVID-19 throughout the United States after February highlights the importance of robust public health systems to respond rapidly to emerging infectious threats.

Dataset Information

Detecting Rapid Spread of SARS-CoV-2 Variants, France, January 26-February 16, 2021.

Publications

Detecting Rapid Spread of SARS-CoV-2 Variants, France, January 26-February 16, 2021.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets