Cerebrospinal fluid leakage after cranial surgery in the pediatric population-a systematic review and meta-analysis.

ABSTRACT:

Background

Cerebrospinal fluid (CSF) leakage is a common complication after neurosurgical intervention. It is associated with substantial morbidity and increased healthcare costs. The current systematic review and meta-analysis aim to quantify the incidence of cerebrospinal fluid leakage in the pediatric population and identify its risk factors.

Methods

The authors followed the PRISMA guidelines. The Embase, PubMed, and Cochrane database were searched for studies reporting CSF leakage after intradural cranial surgery in patients up to 18 years old. Meta-analysis of incidences was performed using a generalized linear mixed model.

Results

Twenty-six articles were included in this systematic review. Data were retrieved of 2929 patients who underwent a total of 3034 intra

SUBMITTER: Slot EMH 

PROVIDER: S-EPMC8084768 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature