Effectiveness and tolerability of a squalane and dimethicone-based treatment for head lice.

ABSTRACT: Head lice (Pediculus humanus capitis) are worldwide obligate human ectoparasites, with high implications in pediatrics. In Europe, first-line topical neurotoxic insecticidal therapeutic strategies are being replaced by topical physically acting agents as the first-choice treatment. Safety of the active ingredients and high efficacy in a one-time single-dose treatment with a brief treatment application time are key issues for consumer use and effective compliance. The aim of this study was to assess the in vitro efficacy of a newly developed squalane and dimethicone-based pediculicidal formula, against motile head lice and eggs after 2 and 5 min immersion in the product, as well as its skin tolerance and acceptability under dermatological and pediatric expert control in children with atopic

SUBMITTER: Martinez de Murguia Fernandez L 

PROVIDER: S-EPMC8084834 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature