Tumor-treating fields (TTFields)-based cocktail therapy: a novel blueprint for glioblastoma treatment.

ABSTRACT: Glioblastoma is one of the most common malignant tumors in the central nervous system. Due to the high plasticity, heterogeneity and complexity of the tumor microenvironment, these tumors are resistant to almost all therapeutic strategies when they reach an advanced stage. Along with being a unique and effective way to kill cancer cells, tumor-treating fields (TTFields) has emerged as a breakthrough among glioblastoma therapies since the advent of temozolomide (TMZ), and the combination of these treatments has gradually been promoted and applied in the clinic. The combination of TTFields with other therapies is particularly suitable for this type of "cold" tumors and has attracted a large amount of attention from clinicians and researchers in the era of cancer cocktail therapy. Here, we in

SUBMITTER: Wang M 

PROVIDER: S-EPMC8085847 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature