First detection of mobilized colistin resistance mcr-1 gene in Escherichia coli isolated from livestock and sewage in Iran.

ABSTRACT: Currently, few studies have investigated the mechanisms of resistance to colistin in Iran. The aim of this study was to investigate mcr-harbouring Escherichia coli dissemination in livestock and sewage in Iran. A total of 115 samples from cows (n = 38), chickens (n = 47) and urban sewage samples (n = 30) were collected. The presence of genes including mcr1-6 and ampC β-lactamase (bla _MOX, bla _CIT, bla _DHA, bla _ACC, bla _EBC, bla _FOX) for colistin-resistant isolates was investigated by multiplex PCR method. Genetic association of colistin-resistant strains was also evaluated by ERIC PCR. Sixty-five isolates were identified as E. coli<

SUBMITTER: Nikkhahi F 

PROVIDER: S-EPMC8086131 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature