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Colonization with multidrug-resistant Enterobacteriaceae among infants: an observational study in southern Sri Lanka.


ABSTRACT:

Background

The timing of and risk factors for intestinal colonization with multidrug-resistant Enterobacteriaceae (MDRE) are still poorly understood in areas with high MDRE carriage. We determined the prevalence, timing, and risk factors associated with MDRE intestinal colonization among infants in southern Sri Lanka.

Methods

Women and their newborn children were enrolled within 48 h after delivery in southern Sri Lanka. Rectal swabs were collected from women and infants at enrollment and 4-6 weeks later. Enterobacteriaceae were isolated and identified as MDRE (positive for extended-spectrum β-lactamases or carbapenem resistant) using standard microbiologic procedures. We used exact methods (Fisher's exact and Kruskal-Wallis tests) and multivariable logistic regression to id

SUBMITTER: Meredith HR 

PROVIDER: S-EPMC8086278 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature