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Hepatitis B virus infection and its determinants among HIV positive pregnant women: Multicenter unmatched case-control study.


ABSTRACT:

Background

Hepatitis B virus (HBV) kills millions of people globally; it is worse in pregnant women. HBV and Human Immune Virus (HIV) co-infection is associated with increased liver diseases such as cirrhosis and hepatocellular carcinoma. This study aimed at identifying the determinants of HBV infection among HIV-positive pregnant women.

Methods

A multicentre unmatched case-control study was conducted among 109 cases (HBV/HIV co-infected) and 327 controls (HIV positive) pregnant women in seven hospitals of the Eastern Amhara region. Interview and chart review data collection techniques were employed by trained personnel. A binary logistic regression model was used to identify independent predictors of hepatitis B virus infection. Variables with a p-value of <0.05 and 95% con

SUBMITTER: Anteneh ZA 

PROVIDER: S-EPMC8087076 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature