Transvalvular Flow Rate Determines Prognostic Value of Aortic Valve Area in Aortic Stenosis.

ABSTRACT:

Background

Aortic valve area (AVA) ≤1.0 cm² is a defining characteristic of severe aortic stenosis (AS). AVA can be underestimated at low transvalvular flow rate. Yet, the impact of flow rate on prognostic value of AVA ≤1.0 cm² is unknown and is not incorporated into AS assessment.

Objectives

This study aimed to evaluate the effect of flow rate on prognostic value of AVA in AS.

Methods

In total, 1,131 patients with moderate or severe AS and complete clinical follow-up were included as part of a longitudinal database. The effect of flow rate (ratio of stroke volume to ejection time) on prognostic value of AVA ≤1.0 cm² for time to death was evaluated, adjusting for confounders. Sensitivity analysis was performed to identify the optimal c

SUBMITTER: Namasivayam M 

PROVIDER: S-EPMC8087111 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature