Short-term exposure to air pollution and biomarkers of cardiovascular effect: A repeated measures study.

ABSTRACT: To help understand the pathophysiologic mechanisms linking air pollutants and cardiovascular disease (CVD), we employed a repeated measures design to investigate the associations of four short-term air pollution exposures - particulate matter less than 2.5 μm in diameter (PM_2.5), nitrogen dioxide (NO₂), ozone (O₃) and sulfur dioxide (SO₂), with two blood markers involved in vascular effects of oxidative stress, soluble lectin-like oxidized LDL receptor-1 (sLOX-1) and nitrite, using data from the Multi-Ethnic Study of Atherosclerosis (MESA). Seven hundred and forty participants with plasma sLOX-1 and nitrite measurements at three exams between 2002 and 2007 were included. Daily PM_2.5, NO₂, O₃ and SO₂ zer

SUBMITTER: Ni Y 

PROVIDER: S-EPMC8087633 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature