Ultra-wide field swept-source optical coherence tomography angiography in patients with diabetes without clinically detectable retinopathy.

ABSTRACT:

Background

To investigate alterations in retinal microvasculature in eyes with preclinical diabetic retinopathy (DR) using ultra-wide field swept-source optical coherence tomography angiography (UWF SS OCTA).

Methods

Prospective cross-sectional study. Fifty-five eyes of 30 diabetic patients without clinical retinal signs were included. All subjects underwent OCTA examination with a 12 × 12 mm² field of view of 5 visual fixations (1 central fixation and 4 peripheral fixations) to compose a UWF OCTA image. In the UWF images, the central area corresponded to the original central image obtained using central fixation, and the peripheral area was the remaining area. Lesions, including nonperfusion areas (NPAs), microvascular dilation and tortuosity, and neovascularizat

SUBMITTER: Yang J 

PROVIDER: S-EPMC8088031 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature