Sex differences in the phylum-level human gut microbiota composition.

ABSTRACT:

Background

Evidence was previously provided for sex-related differences in the human gut microbiota composition, and sex-specific discrepancy in hormonal profiles was proposed as a main determinant of these differences. On the basis of these findings, the assumption was made on the role of microbiota in the sexual dimorphism of human diseases. To date, sex differences in fecal microbiota were demonstrated primarily at lower taxonomic levels, whereas phylum-level differences between sexes were reported in few studies only. In the present population-based cross-sectional research, sex differences in the phylum-level human gut microbiota composition were identified in a large (total n = 2301) sample of relatively healthy individuals from Ukraine.

Results

Relative abundances of

SUBMITTER: Koliada A 

PROVIDER: S-EPMC8088078 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature