The Influence of Cataract on Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO).

ABSTRACT:

Purpose

To investigate the influence of lens opacifications on fluorescence lifetime imaging ophthalmoscopy (FLIO).

Methods

Forty-seven eyes of 45 patients were included. Mean fluorescence lifetimes (Tm) were recorded with a fluorescence lifetime imaging ophthalmoscope in a short spectral channel (SSC) and a long spectral channel (LSC). Retinal and lens autofluorescence lifetimes were measured in subjects before and after cataract surgery. Lens opacification was graded using the Lens Opacities Classification System III (LOCS III) classification.

Results

The retinal Tm decreased significantly after cataract surgery in both spectral channels (SSC: -53%, P < 0.0001; LSC: -26%, P = 0.0041). The lens Tm differed significantly between the crystalline and the artificial lens

SUBMITTER: Lincke JB 

PROVIDER: S-EPMC8088233 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature